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Sensitization to Molds and Respiratory Symptoms in School Children
Taskinen1 T., M.D., Hyvärinen A., M.Sc., Meklin T., M.Sc., Husman T., M.D.,
Nevalainen A., Ph.D., Korppi1 M. M.D.
Kuopio University Hospital, E-mail: Taina.Taskinen@ktl.fi, taina.taskinen@kiuruvesi.fi
We performed a questionnaire study in 622 school children; asthma or asthmatic
symptoms were present in 208 (33%) children. Moisture and mold problems
weredocumented in the index school (N=414; 168 (41%) were symptomatic); the
control school (N=208; 40 (19%) were symptomatic, p<0.001) had no such problems.
Skin prick tests to 13 molds (9 occurring in environment and 4 indicating
moisture problems in buildings) were performed in the 208 symptomatic children.
A positive reaction (>3mm) was observed in only 5 (2%) children. Children who
were exposed to molds in the school had more often emergency visits (OR=2.0,
p<0.01) and also they had used more antibiotic courses (OR=2.1, p<0.01) than
nonexposed pupils, but only during spring. Our results show that skin test
positivity to molds is rare in school children. This is true in pupils with
asthmatic symptoms, and also in the pupils from the school with moisture or mold
problems. In addition, respiratory infections seem to be associated with mold
exposure.