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Airborne Concentrations of Trichoderma and Stachybotrys linked to Mycotoxicosis
Larry D. Robertson, M.S., B.S. Mycotech Biological, Inc., Jewett, TX
The affected individual developed symptoms approximately 55 days after exposure
to a working environment containing significant fungal contamination. Initial
symptoms included bronchitis, swelling, spastic colon, severe headaches, and
fatigue. Later, abdominal pain, nausea, diarrhea, and loose teeth were reported.
Three physicians having specialties in internal medicine, toxicology, and
neurology independently diagnosed exposure to an "unknown" environmental toxin;
however, the physicians were not provided with environmental results from the
work place. The work environment indicated airborne concentrations of
Trichoderma viride and Stachybotrys chartarum at 494 CFU/m3 and 212 CFU/m3,
respectively. Active Trichoderma viride and Stachybotrys chartarum growth sites
were documented at levels of 3.3 x 104 CFU/g and 2.0 x 107 CFU/g; respectively.
Although these contaminants were exclusive to the individuals work area, the CIH/CSP
represented the data as "typical" for indoor environments. As a result, no
exposure data was provided to the attending physicians. After 5 months of
exposure the individual became too ill to return to work. Within 1 month of
removal the symptoms begin to subside. Complete symptom cessation resulted after
12 months. The absence of specific human dose-exposure data relative to the
various mycotoxins produced by Trichoderma viride and Stachybotrys chartarum
does not support a valid medical claim relative to an aerosol-induced
mycotoxicosis. However, anecdotal, circumstantial, and environmental information
strongly supports the potential for this event to have occurred. This study
demonstrates the current void that exists relative to both the knowledge and
availability of mycotoxin diagnostic methods in the medical field and suggests
the immediate need for education, training, and research relative to aerosol
generated mycotoxicoses.